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This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies as a new emerging specialty. Management of peritoneal surface malignancies (PSM) differs completely from treatment of intra-abdominal cancers at early stages and these approaches are included here.§Combined treatment of cytoreductive surgery (CRS) and hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) introduced by Paul H. Sugarbaker are performed to treat peritoneal metastases (PM) by surgeons all over the world. This book is focused on detailed surgical anatomy of the peritoneum, preoperatice clinical assessment of the peritoneal surface malignancy, patient preparation and operation room equipment, different surgical procedures for CRS and reconstruction, intraoperatice HIPEC and neoadjuvant intraperitoneal chemotherapy, early postoperative intraperitoneal chemotherapy (EPIC) and molecular basis of peritoneal surface malignancies.§§