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This practical volume is intended for all radiologists, gastroenterologists, and surgeons who are responsible for or interested in the diagnosis and care of patients with diseases of the anal and perianal region. After an introductory chapter focusing on surgical, MRI, and US anatomy, up-to-date clinical and therapeutic information is provided on the full range of perianal inflammatory conditions, with special attention to Crohn s disease, ulcerative colitis, and sexually transmitted diseases. Physical and surgical examination is carefully discussed, with consideration of limitations, results, clinical needs, and the questions likely to be posed of imaging. The subsequent three chapters provide detailed information on the role of state of the art imaging modalities: transanal and transperineal ultrasound, contrast-enhanced MRI, and CT. Techniques, diagnostic accuracy, common and unusual disease patterns, artifacts, and pitfalls are clearly presented. The book concludes by proposing a practical diagnostic algorithm with integration of the different imaging modalities.