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This book serves as a clinical guide for select endodontic topics and treatment procedures. Its focus is on the ways in which various factors, and the treatment procedures themselves, impact on the short- and long-term outcome of endodontic treatment. The book incorporates the most up-to-date knowledge, techniques, and treatment protocols. Each chapter has been carefully chosen to address either foundational knowledge or a particular aspect of endodontic treatment that may affect the outcome. The authors summarize what has been learned from a large number of outcome studies and short- and long-term follow-ups, and provide critical appraisals of those studies. Recommendations are then made on how that information can be used to predict the outcome of the intended treatment. Using this book, the reader will be able to assess the prognosis of the proposed treatment at the outset and thus to plan treatment with the optimal outcome in mind.