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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volumes covers protein kinase inhibitors in research and medicine, and includes chapters on such topics as fragment-based screening, broad kinome profiling of kinase inhibitors, and designing drug-resistant kinase alleles. * Continues the legacy of this premier serial with quality chapters authored by leaders in the field * Covers research methods in biomineralization science* Contains sections focusing on protein kinase inhibitors in research and medicine