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Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies. §This book should be useful for immunologists, molecular biologists, rheumatologists, and clinical scientists.

About the book

Full name Mechanisms of Lymphocyte Activation and Immune Regulation VIII
Author Sudhir Gupta
Language English
Binding Book - Paperback
Date of issue 2012
Number of pages 136
EAN 9781461354581
ISBN 1461354587
Libristo code 06796367
Weight 237
Dimensions 155 x 235 x 9
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