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This work identifies and discusses critical issues of ICT innovation at both the macroeconomic and organizational levels, bringing together two hitherto independent fields of study: economics and information systems. The book takes stock of these two fields, highlighting their complementarity in contemporary issues such as business competitiveness and e-commerce, organizational change and industrial restructuring, information systems implementation and technology infrastructure building. The contributions cover a broad range of issues, from analysing policy approaches for fostering ICT innovation at a regional level, to examining the way in which ICT-based information systems and organizational practice are simultaneously shaped.