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Genome Instability in Cancer Development

Language EnglishEnglish
Book Hardback
Book Genome Instability in Cancer Development E. A. Nigg
Libristo code: 01416302
Publishers Springer-Verlag New York Inc., October 2005
This book reviews both genetic and biochemical data on the origin of genome instability and its impa... Full description
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This book reviews both genetic and biochemical data on the origin of genome instability and its impact on carcinogenesis. Reflecting recent discoveries and ongoing research, it discusses DNA repair mechanisms and hereditary cancer syndromes, as well as checkpoint mechanisms operating to safeguard chromosome integrity during cell cycle progression. Moreover, it summarises our current understanding of the various defects that may allow cancer cells to rapidly accumulate critical mutations and evolve, through processes reminiscent of Darwinian selection, an increasingly aggressive behaviour. Hopefully, this book will stimulate thought, discussion and experimentation, and serve as a rich source of information for a wide audience, including advanced students, researchers and clinical oncologists.

About the book

Full name Genome Instability in Cancer Development
Author E. A. Nigg
Language English
Binding Book - Hardback
Date of issue 2005
Number of pages 512
EAN 9781402037634
ISBN 1402037635
Libristo code 01416302
Weight 1299
Dimensions 183 x 260 x 37
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