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This volume is both a comprehensive assessment of current approaches to management of diabetic pregnancy and a forum for discussion of alternative treatment protocols. Thyroid dysfunction and diabetic retinopathy during pregnancy, prevention of congenital malformations in infants of diabetic mothers, and the metabolic sequelae in these infants are explored, as are such controversial matters as the use of fetal pancreatic tissue for transplantation, of exercise during pregnancy, and of the oral hypoglycemic agents. The contributions significantly enhance our understanding of maternal, fetal and neonatal physiology under normal conditions and in pregnancies complicated by diabetes.